Anchored Design of Protein-Protein Interfaces
نویسندگان
چکیده
منابع مشابه
Anchored Design of Protein-Protein Interfaces
BACKGROUND Few existing protein-protein interface design methods allow for extensive backbone rearrangements during the design process. There is also a dichotomy between redesign methods, which take advantage of the native interface, and de novo methods, which produce novel binders. METHODOLOGY Here, we propose a new method for designing novel protein reagents that combines advantages of rede...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2011
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0020872